A review and analysis of empirical and historical evidence pertaining to tobacco and food industry practices, messages, and strategies to influence public opinion, legislation and regulation, litigation, and the conduct of science. The tobacco industry had a playbook, a script, that emphasized personal responsibility, paying scientists who delivered research that instilled doubt, criticizing the ‘œjunk’ science that found harms associated with smoking, making self-regulatory pledges, lobbying with massive resources to stifle government action, introducing ‘œsafer’ products, and simultaneously manipulating and denying both the addictive nature of their products and their marketing to children. The script of the food industry is both similar to and different from the tobacco industry script. See alsohttp://www.fooducate.com/blog/2009/03/17/the-food-industry-is-not-behaving-like-the-tobacco-industry-right/